A VERSATILE ENDOSOME ACIDITY-INDUCED SHEDDABLE GENE DELIVERY SYSTEM: INCREASED TUMOR TARGETING AND ENHANCED TRANSFECTION EFFICIENCY

A versatile endosome acidity-induced sheddable gene delivery system: increased tumor targeting and enhanced transfection efficiency

Ming Zhao, Ji Li, Hongrui Ji, Dawei Chen, Haiyang HuDepartment of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang 110016, People’s Republic of ChinaBackground: Polycation carriers show great foreground in the developing efficient and safe gene delivery; nevertheless, they are cytotoxic and unstable in vivo beca

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A Simple and Versatile Concept to Improve Dynamic Range and Enable Target Angle Adaptability in Radar Target Simulators

Radar target simulators are not only a critical tool for verifying and testing radar systems but also play an important role in supporting the development of self-driving cars.Advances in radar sensors and techniques raise the required specifications for these units, increasing their complexity and cost.This article presents a novel and universal c

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Two Conservative Difference Schemes for Rosenau-Kawahara Equation

Two Pipes conservative finite difference schemes for the numerical solution of the initialboundary value problem of Rosenau-Kawahara equation are proposed.The difference schemes simulate two conservative quantities of the problem Custom Made Halters well.The existence and uniqueness of the difference solution are proved.It is shown that the finite

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VIGS in afrika, met spesiale verwysing na Suid-Afrika

It is generally accepted that Africa is the continent that is most seriously affected by the AIDS epidemic.As a result of under-reporting, the actual incidence of AIDS may be more than ten times higher than indicated by the official Oven Door Cap figures.The majority of females of child-bearing age can be infected within the next 4-6 years.Infant m

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